Research. Insights. Real talk on genomics.
Science-first content from the researchers building the tools.
How Much Coverage Do You Need for Long-Read Low-Pass Sequencing?
The answer to 'how much coverage do I need' depends on your species, your study question, and which variant classes matter to you. This guide breaks it down so you can design a study that works.
The Real Cost of Sequencing: What Per-Sample Price Doesn't Tell You
Per-sample price is how sequencing gets sold but it's not how discoveries get made. This post reframes the economics of genomics research from the ground up.
Why Can't Short-Read Sequencing Resolve Polyploid Genomes?
Short-read sequencing cannot distinguish between the duplicated chromosomes that define polyploid genomes. Here is what that failure costs — and why long-read low-pass sequencing resolves it.
Long-Read vs. Short-Read Sequencing: Which Should You Use?
Long-read and short-read sequencing are not competing technologies for the same job. Here is how to choose the right method for your research question.