Research, insights, real talk on genomics.
Science-first content from the researchers building the tools.
How do You Build a Better Reference Panel for Genotype Imputation?
A reference panel sets the ceiling on imputation accuracy. Walid Korani, PhD, explains why panels built from arrays and short reads underperform, how long reads change panel construction, and a practical framework for building one that holds up in diverse populations.
How Long-Read Low-Pass Sequencing Works in a Pangenome Study
A single reference genome captures one individual's biology — everything else in the population reads as deviation. Here's how long-read low-pass sequencing paired with pangenome graphs recovers the variation standard sequencing misses, and when you actually need it.